Expression data from differentiating ES cells expressing Snail during Wnt inhibition

GSE24291

Mus musculus

4 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

ES cells differentiated in the presence of the Wnt inhibitor DKK1 fail to express the transcription factor Snail and undergo EMT. We generated an ES cell line, A2.snail, that induced Snail expression upon addition of doxycycline addition.

PubMed ID

21394833

Publication Title

Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs.

Total Samples

Submitter’s Institution

Washington University School of Medicine

Authors

Gill JG, Langer EM, Lindsley RC, Cai M, Murphy TL, Kyba M, Murphy KM

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-24291

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