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accession-icon GSE16104
IL-1b responses in receptor-reconstituted AcP-deficient neurons
  • organism-icon Mus musculus
  • sample-icon 22 Downloadable Samples
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Description

The purpose was to determine AcP- and AcPb-dependent gene responses to IL-1 by virally-reconstituting AcP-deficient mouse embryonic cortical neurons with CD25 (control), full length AcP, AcPb or the combination of both. A control population was transduced with a CD25-expressing virus. Half the samples were stimulated with IL-1-beta for four hours, RNA was analyzed by microarray.

Publication Title

A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1.

Alternate Accession IDs

E-GEOD-16104

Sample Metadata Fields

Specimen part

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accession-icon GSE23780
A Novel Statistical Algorithm for Gene Expression Analysis Differentiates PXR-Dependent and Independent Mechanisms of Toxicity
  • organism-icon Mus musculus
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon

Description

The objective of the present study is to examine the potential role of the pregnane x receptor (PXR) in mice treated with an small molecule inhibitor for beta-secretase (CMP013)

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-23780

Sample Metadata Fields

Specimen part, Treatment

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