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GSE24489
Mus musculus
13 Downloadable Samples
Description
The expression of the small molecular weight heat shock protein (Hsp) H11 kinase/Hsp22 (Hsp22) is restricted to a limited number of tissues, including the heart and skeletal muscle, both in rodents and in humans. We generated a mouse knockout (KO) model, and investigated the role of Hsp22 in regulating cardiac hypertrophy in response to pressure overload. We compared gene expression profiles between WT and KO mice in basal condition and three days pressure overload after transverse aortic constriction (TAC). These data illustrated a novel mechanism of Hsp22-related gene expression in response to cardiac stress.
Publication Title
H11 kinase/heat shock protein 22 deletion impairs both nuclear and mitochondrial functions of STAT3 and accelerates the transition into heart failure on cardiac overload.
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Sex, Specimen part
View Samples- Danio rerio
- 3 Downloadable Samples
Description
Microarray data allowed detection of genes that are highly expressed in the pineal gland.
Publication Title
A new cis-acting regulatory element driving gene expression in the zebrafish pineal gland.
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