Description

Metabolically active cells require robust mechanisms to combat oxidative stress. The cytoplasmic thioredoxin reductase/thioredoxin (Txnrd1/Txn1) system maintains reduced protein dithiols and provides electrons to some cellular reductases, including peroxiredoxins.

Publication Title

Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes.

Alternate Accession IDs

E-GEOD-16381

Sample Metadata Fields

Specimen part