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Accession IconGSE7762

Morphine effects on striatal transcriptome in four inbred mouse strains

Organism Icon Mus musculus
Sample Icon 1 Downloadable Sample
Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

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Chronic opiate use produces molecular and cellular adaptations in the nervous system, leading to tolerance, physical dependence and addiction. Genome-wide comparison of morphine-induced changes in brain transcription of mouse strains with different opioid-related phenotypes provides an opportunity to discover the relationship between gene expression and behavioral response to the drug.
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