Liver expression data from 31 mouse strains treated with vehicle or isoniazid for 3 days

GSE55489

Mus musculus

215 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Isoniazid induced varying degrees of hepatic steatosis in an inbred strain Mouse Diversity Panel (MDP) study. RNA was isolated from all animals for analysis of gene expression changes in the liver. The objective of this study was to identify gene expression changes that drive isoniazid-induced steatosis.

PubMed ID

24848797

Publication Title

A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.

Total Samples

235

Submitter’s Institution

The Hamner Institutes for Health Sciences

Authors

Church RJ, Wu H, Mosedale M, Sumner SJ, Pathmasiri W, Kurtz CL, Pletcher MT, Eaddy JS, Pandher K, Singer M, Batheja A, Watkins PB, Adkins K, Harrill AH

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-55489

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