Expression data from adult mouse normal and damaged retina from B6 and 129 mouse strains

Retinal damage causes proliferation of Muller glia, but the degree of proliferation depends on mouse strains. Muller glial proliferation was significantly promoted by the addition of GSK3 inhibitor in 129, but not in B6. We used retinal explant culture as a model for retinal damage which caused preferential photoreceptor death in a few days.

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Suga A, Sadamoto K, Fujii M, Mandai M, Takahashi M