Microarray profiling of STEP knockout mouse striatum

STEP (striatal-enriched tyrosine phosphatase) is a brain-specific phosphatase named for its robust expression in striatum. Brains from homozygous and heterozygous STEP knockout mice and wild-type littermates were harvested, and striatum microdissected. RNA was extracted and hybridized to Affymetrix 230_2 microarray chips.

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Reinhart VL, Nguyen T, Gerwien R Jr, Kuhn M, Yates PD, Lanz TA