Gene expression data from livers of Yap+/+ and Yap+/- mice at postnatal day 30

Liver undergoes both size increase and differentiation during postnatal period, which in mice is approximately first 30 days. The mechanisms of simultaneous postnatal liver cell proliferation and maturation are not clear. In these experiments, role of yes associated protein (Yap), the downstream effector of Hippo Kinase signaling pathway was investigated.

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Septer S, Edwards G, Gunewardena S, Wolfe A, Li H, Daniel J, Apte U