Expression data from MALP-2-stimulated macrophages from wild-type, IRAK-2-/- and IRAK-1-/IRAK-2-/- mice

GSE10765

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

IL-1R-associated kinases (IRAKs) participate in Toll-like receptor (TLR) signal transduction. MALP-2 is a TLR2 ligand, and stimulation of macrophages with MALP-2 activates expression of various genes including proinflammatory cytokines.

PubMed ID

18438411

Publication Title

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

Total Samples

Submitter’s Institution

Kyoto University

Authors

Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Saitoh T, Kawai T, Takeuchi O, Akira S

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-10765

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