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Homo sapiens (6)

Mus musculus (6)

Technology

Microarray (6)

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Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2) (6)

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GSE15969

Changes in gene expression of hMSCs and NOD/scid mouse lung after IV infusion of hMSCs

Mus musculus, Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Quantitative assays for human DNA and mRNA were used to examine the paradox that intravenously (IV) infused human multipotent stromal cells (hMSCs) can enhance tissue repair without significant engraftment. After 2 X 106 hMSCs were IV infused into mice, most of the cells were trapped as emboli in l ...See More

Publication Title

Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6.

Alternate Accession IDs

E-GEOD-15969

Sample Metadata Fields

Specimen part, Disease

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