Filters
Organism
Technology
Platforms
Description
To understand the underlying cause for the observed apoptosis in E2f1-3 deficient myeloid cells. We compared gene expression profiles of Cd11b+ sorted myeloid cells isolated from bone marrow of control (E2F1-/- ) and experimental (Mxcre;E2F1-/-2-/-3f/f ) mice.
Publication Title
E2f1-3 are critical for myeloid development.
Alternate Accession IDs
E-GEOD-25825Sample Metadata Fields
Age, Specimen part
Description
Psoriasin (S100A7) has been shown to be highly expressed in invasive estrogen receptor negative breast cancers. Expression of S100A7 in human breast tumors represents a poor prognostic marker and correlates with lymphocyte infiltration in high-grade morphology. Recent studies have shown that S100A7 ...See More
Publication Title
S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.
Alternate Accession IDs
E-GEOD-32052Sample Metadata Fields
Cell line
Description
The majority of NK cells (~90%) are phenotypically characterized as CD56dimCD16+, while the remaining are CD56brightCD16-. The cytotoxic CD56dimCD16+ NK subset expresses higher levels of chemokine receptors, and therefore is preferentially recruited to sites of inflammation. Encounters between CD56d ...See More
Publication Title
Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12.
Alternate Accession IDs
E-GEOD-63038Sample Metadata Fields
Specimen part, Subject
Description
Detailed analysis of genome-wide transcriptome profiling in rice root is reported here, following Cr-plant interaction. Such studies are important for the identification of genes responsible for tolerance, accumulation and defense response in plants with respect to Cr stress. Rice root metabolome an ...See More
Publication Title
Transcriptomic and metabolomic shifts in rice roots in response to Cr (VI) stress.
Alternate Accession IDs
E-GEOD-25206Sample Metadata Fields
Age, Specimen part, Treatment
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Canonical and atypical E2Fs regulate the mammalian endocycle.
Alternate Accession IDs
E-GEOD-32355Sample Metadata Fields
Age, Specimen part
Description
To understand the underlying cause and mechanisms of changes in hepatocyte ploidy upon Albumin-Cre mediated deletion of E2f7&8 and Mx1-Cre mediated deletion of E2f1,2&3, we analysed global gene expression of 6 weeks and 2 months liver tissues.
Publication Title
Canonical and atypical E2Fs regulate the mammalian endocycle.
Alternate Accession IDs
E-GEOD-32354Sample Metadata Fields
Age, Specimen part
Description
The development of complex tissues requires that mitotic progenitor cells integrate information from the environment. The highly varied outcomes of such integration processes undoubtedly depend at least in part upon variations among the gene expression programs of individual progenitor cells. To dat ...See More
Publication Title
Individual retinal progenitor cells display extensive heterogeneity of gene expression.
Alternate Accession IDs
E-GEOD-9811Sample Metadata Fields
Specimen part
Description
We used oligonucleotide microarrays to address the specificities of transcriptional responses of adult Drosophila to different stresses induced by paraquat and H2O2, two oxidative stressors, and by tunicamycin which induces an endoplasmic reticulum (ER) stress. Flies were tested 24 hours after expos ...See More
Publication Title
Genome wide analysis of common and specific stress responses in adult drosophila melanogaster.
Alternate Accession IDs
NoneSample Metadata Fields
Sex, Age, Compound, Time
Description
Analysis of whole heart samples from Hdac3-Isl1KO embryos at embryonic day E9.5. Results provide insights into the role of Hdac3 in second heart field-derived cardiac cells.
Publication Title
Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development.
Alternate Accession IDs
E-GEOD-73666Sample Metadata Fields
Specimen part
Description
Identification of genes expressed in a preferential manner in the developing ciliary body/iris will provide a starting point for future functional analyses. To identify candidate genes expressed in a variety of ocular tissues during development, we have profiled single cells from the developing eye ...See More
Publication Title
Identification of genes expressed preferentially in the developing peripheral margin of the optic cup.
Alternate Accession IDs
E-GEOD-15566Sample Metadata Fields
Specimen part