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This SuperSeries is composed of the SubSeries listed below.
Publication Title
MicroRNA-mRNA interactions in a murine model of hyperoxia-induced bronchopulmonary dysplasia.
Alternate Accession IDs
E-GEOD-25293Sample Metadata Fields
Specimen part, Disease, Disease stage, Treatment
Description
The goal of the was to evaluate the mRNA expression profile of non-asthmatic and asthmatic airway smooth muscle. Overall design: RNA Seq was performed on nonasthmatic (n=5 individuals) and asthmatic (n=5 individuals) human airway smooth muscle cells.
Publication Title
Arhgef12 drives IL17A-induced airway contractility and airway hyperresponsiveness in mice.
Alternate Accession IDs
GSE119578Sample Metadata Fields
Sex, Age, Specimen part, Disease, Subject
Description
To analyze target genes of human heat shock transcription factor 1 (HSF1), we first generated two independent HeLa clones (RDT1 and RDT2) expressing an actively mutated hHSF1 (hHSF1RDT), which lacks the regulatory domain that masks its activation domain and possesses a glutamic acid at amino acid 39 ...See More
Publication Title
Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.
Alternate Accession IDs
E-GEOD-19797Sample Metadata Fields
Cell line
Description
Transcription factor access to regulatory elements is prevented by the nucleosome. Heat shock factor 1 (HSF1) is a winged helix transcription factor that plays roles in control and stressed conditions by gaining access to target elements, but mechanisms of HSF1 access have not been well known in mam ...See More
Publication Title
RPA assists HSF1 access to nucleosomal DNA by recruiting histone chaperone FACT.
Alternate Accession IDs
E-GEOD-38412Sample Metadata Fields
Specimen part
Description
Clinical study of critically ill patients with sepsis and sepsis-related ARDS with whole blood RNA collected within the first 24 hours of admission
Publication Title
Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.
Alternate Accession IDs
E-GEOD-66890Sample Metadata Fields
Sex, Disease, Disease stage
Description
To clarify inflammatory genes whose expression is suppressed at high temperatures, we performed comprehensive analysis of gene expression by using a DNA microarray. Two independent primary cultures of mouse embryo fibroblasts (MEF1 and MEF2) were treated with LPS for 4 hours, or treated with LPS for ...See More
Publication Title
Heat shock transcription factor 1 inhibits expression of IL-6 through activating transcription factor 3.
Alternate Accession IDs
E-GEOD-16266Sample Metadata Fields
Specimen part
Description
Cotton is one of the most commercially important Fiber crops in the world and used as a source for natural textile Fiber and cottonseed oil. The fuzzless-lintless ovules of cotton mutants are ideal source for identifying genes involved in Fiber development by comparing with Fiber bearing ovules of w ...See More
Publication Title
Functional genomics of fuzzless-lintless mutant of Gossypium hirsutum L. cv. MCU5 reveal key genes and pathways involved in cotton fibre initiation and elongation.
Alternate Accession IDs
E-GEOD-38490Sample Metadata Fields
Specimen part
Description
Samples were taken from colorectal cancers in surgically resected specimens in 290 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133Plus 2.0 arrays. The training set of our prognosis classifier included the stage A and D samples. Validation used o ...See More
Publication Title
Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer.
Alternate Accession IDs
E-GEOD-14333Sample Metadata Fields
No sample metadata fields
Description
WNT1/beta-catenin signaling plays a crucial role in the generation of mesodiencephalic dopaminergic (mdDA) neurons including the Substantia nigra pars compacta (SNc) subpopulation, whose degeneration is a hallmark of Parkinsons Disease (PD). However, the precise functions of WNT/beta-catenin signali ...See More
Publication Title
Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse.
Alternate Accession IDs
E-GEOD-58813Sample Metadata Fields
Specimen part
Description
IPF (n=20) and control (n=19) samples were obtained through the LTRC and were sequenced on an Illumina HiSeq 2000 following TruSeq RNA Sample Prep Kit v2 library preparation. Overall design: Cross-sectional samples were analyzed. IPF diagnosis was based on American Thoracic Society and European Resp ...See More
Publication Title
Cellular senescence mediates fibrotic pulmonary disease.
Alternate Accession IDs
GSE92592Sample Metadata Fields
Specimen part, Disease, Disease stage, Subject