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Description
All highly and poorly permeable metastases from the same mouse brain were collected by laser capture microdissection. Total RNA from both metastatic lesions and immediate microenvironment was isolated from 5 mice bearing 231-BR metastases. As control 4 healthy mouse brains were included.
Publication Title
Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases.
Alternate Accession IDs
E-GEOD-112776Sample Metadata Fields
Subject
Fat Treg cells
Description
Comparisons of global gene-expression profiles revealed a greater distinction between CD4+ Treg cells and CD4+ conventional (Tconv) T cells residing in abdominal (epidydimal) fat versus in more standard locations such as the spleen, thymus and LN.
Publication Title
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.
Alternate Accession IDs
E-GEOD-7852Sample Metadata Fields
Specimen part
Description
Regulation of homeostasis and development of cardiac muscle tissues is controlled by a core set of transcription factors. The MEF2 family plays a critical role in these processes.
Publication Title
Antagonistic regulation of cell-cycle and differentiation gene programs in neonatal cardiomyocytes by homologous MEF2 transcription factors.
Alternate Accession IDs
E-GEOD-92861Sample Metadata Fields
Specimen part
Description
In this study, we have identified MEF2A-sensitive genes in atrial and ventricular chambers of the adult heart. MEF2A is a member of the myocyte enhancer factor 2 (MEF2) family of transcription factors. MEF2 proteins are expressed in skeletal and cardiac muscle tissues and are conserved across many m ...See More
Publication Title
The transcription factor MEF2A fine-tunes gene expression in the atrial and ventricular chambers of the adult heart.
Alternate Accession IDs
E-GEOD-95364Sample Metadata Fields
Specimen part
Description
The spliceosome is a dynamic RNA-protein complex that executes pre-mRNA splicing and is composed of five core small nuclear ribonucleoprotein particles (U1, U2, U4/5/6 snRNP) and >150 additional proteins specific for each snRNP. We report a circadian role for Pre-mRNA Processing factor 4 (PRP4), a c ...See More
Publication Title
Spliceosome factors target timeless (<i>tim</i>) mRNA to control clock protein accumulation and circadian behavior in Drosophila.
Alternate Accession IDs
GSE115163Sample Metadata Fields
Specimen part, Subject
Description
RNAi mediated suppression of MADS29 severely affects seed set; the surviving seeds are smaller in size with reduced grain filling, abnormal starch grains and aberrant embryo development. To identify the affected pathways due to suppression of this transcription factor in the transgenic seeds, trans ...See More
Publication Title
Functional delineation of rice MADS29 reveals its role in embryo and endosperm development by affecting hormone homeostasis.
Alternate Accession IDs
E-GEOD-42029Sample Metadata Fields
Specimen part
Description
Overexpression of MADS29 results in severely dwarfed phenotype, resulting from a shift in auxin-cytokinin ratio in favor of cytokinins. To see the extent of change in gene expression in the leaves of the transgenic plants, whole genome transcript analysis was carried out using microarray.
Publication Title
Functional delineation of rice MADS29 reveals its role in embryo and endosperm development by affecting hormone homeostasis.
Alternate Accession IDs
E-GEOD-42028Sample Metadata Fields
Specimen part
Description
We used microarrays to examine gene expression levels from 95 unrelated CEPH-Utah individuals 0, 2 or 6 hours after treatment with 10Gy of ionizing radiation.
Publication Title
Stress-induced changes in gene interactions in human cells.
Alternate Accession IDs
E-GEOD-36910Sample Metadata Fields
Cell line, Treatment, Time
Description
We used microarrays to examine gene expression levels from 131 unrelated CEPH-Utah grandparents with either DMSO or tunicamycin.
Publication Title
Stress-induced changes in gene interactions in human cells.
Alternate Accession IDs
E-GEOD-36911Sample Metadata Fields
Cell line, Treatment, Time
Description
We used Affymetrix microarray analyses of thirty-two individual Vitis vinifera cv. Cabernet Sauvignon berries sampled from two clusters at fifty-percent ripening initiation. By delineating four developmental stages of ripening initiation, we demonstrate that color is a statistically significant ind ...See More
Publication Title
Gene expression analyses in individual grape (Vitis vinifera L.) berries during ripening initiation reveal that pigmentation intensity is a valid indicator of developmental staging within the cluster.
Alternate Accession IDs
E-GEOD-11406Sample Metadata Fields
No sample metadata fields