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Description
Microarray-based DNA methylation and gene expression profiling was carried out using a panel of prostate cancer cell lines (LNCaP-FGC, DU-145, and PC-3) and the control normal prostate RWPE1 cell line. The identification of prostate cancer-specific methylation markers was based on the following crit ...See More
Publication Title
EFEMP1 as a novel DNA methylation marker for prostate cancer: array-based DNA methylation and expression profiling.
Alternate Accession IDs
E-GEOD-23388Sample Metadata Fields
Specimen part, Cell line
Description
The objective of this study is to identify gene signature associated with castration-refractory prostate cancer (CRPC) development. We carried out RNA-seq based transcriptome profiling using 45 prostate samples with various disease progression steps such as benign prostate hyperplasia (BPH), primary ...See More
Publication Title
Transcriptomic features of primary prostate cancer and their prognostic relevance to castration-resistant prostate cancer.
Alternate Accession IDs
GSE80609Sample Metadata Fields
Subject
Description
There are clear phenotypic differences between Korean native pig (KNP) and Yorkshire (YS) breeds because of different interests for selection. YS has been artificially selected by industrial interests such as a growth rate and a lean meat production, however, KNP has been maintained as a regional br ...See More
Publication Title
Differences in hepatic gene expression as a major distinguishing factor between Korean native pig and Yorkshire.
Alternate Accession IDs
E-GEOD-21408Sample Metadata Fields
Age, Specimen part
Description
To understand epigenetic changes in the distal regulatory as well as proximal regions, we performed RNA-seq, MBD-seq, and H3K27ac ChIP-seq on gastric tissues and cell lines. Overall design: mRNA sequencing profiles of normal tissue (n), purified gastric cancer (sc), and cultured gastric cancer cell ...See More
Publication Title
Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer.
Alternate Accession IDs
GSE46597Sample Metadata Fields
No sample metadata fields
Description
The pig could be a useful model to characterize molecular aspects determining several delicate phenotypes because they have been bred for those characteristics. The Korean native pig (KNP) is a regional breed in Korea that was characterized by relatively high intramuscular fat content and reddish me ...See More
Publication Title
Transcriptional alteration of p53 related processes as a key factor for skeletal muscle characteristics in Sus scrofa.
Alternate Accession IDs
E-GEOD-18653Sample Metadata Fields
Age, Specimen part
Description
In order to investigate the role of reptin methylation on the expression of hypoxia-responsive genes across the whole genome, we performed a microarray analysis from RNAs isolated from MCF7 cells expressing either control shRNA (shRNA) or reptin shRNA (shreptin) in normoxic and hypoxic conditions.
Publication Title
Negative regulation of hypoxic responses via induced Reptin methylation.
Alternate Accession IDs
E-GEOD-15530Sample Metadata Fields
Specimen part, Cell line
Description
We established PDX lines from diffuse type gastric cancers (DGCs). Using these cells, we carried out RNA-seq based transcriptome profiling using 15 stomach samples including three PDX lines (HGC-3, HGC-8, and HGC-20) and normal-looking surrounding tissues. Via comparative analysis between cells and ...See More
Publication Title
Identification of a molecular signature of prognostic subtypes in diffuse-type gastric cancer.
Alternate Accession IDs
GSE106338Sample Metadata Fields
Subject
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
Alternate Accession IDs
E-GEOD-71874Sample Metadata Fields
Sex, Specimen part
Description
RNA-sequencing results with in vitro cultured control and Lats1/2 deficient hepatoblasts, in vitro differentiated control and Lats1/2 deficient hepatocytes and biliary epithelial cells Overall design: To investigate changes in gene expression by loss of Lats1 and Lats2 during hepatocyte or biliary e ...See More
Publication Title
LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
Alternate Accession IDs
GSE71873Sample Metadata Fields
No sample metadata fields
Description
Lats1-/-;Lats2fl/fl;Alb-Cre pups and control pups were sacrificed at 1 day after birth
Publication Title
LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
Alternate Accession IDs
E-GEOD-71872Sample Metadata Fields
Sex, Specimen part