Filters
Organism
Technology
Platforms
Description
Cell lines geneticially engineered to undergo conditional asymmetric self-renewal were used to identify genes whose expression is asymmetric self-renewal associated (ASRA). Non-random sister chromatid segregation occurs concordantly with asymmetric self-renewal in these cell lines.
Publication Title
A resource for discovering specific and universal biomarkers for distributed stem cells.
Alternate Accession IDs
E-GEOD-25334Sample Metadata Fields
Cell line
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
DEMETER plant DNA demethylase induces antiviral response by interferon signalling in animal cells.
Alternate Accession IDs
E-GEOD-96866Sample Metadata Fields
Specimen part, Time
Description
Expression profiles of human embryonic kidney (HEK)-293T cells expressing a GFP (293T-GFP) or a truncated form of Arabidopsis DEMETER (DME) 5-methylcytosine (5mC) DNA glycosylase (293T-DME) analyzed on an Affymetrix Human Genome U133 Plus 2.0 Array Platform. These array data revealed differentially ...See More
Publication Title
DEMETER plant DNA demethylase induces antiviral response by interferon signalling in animal cells.
Alternate Accession IDs
E-GEOD-96863Sample Metadata Fields
Specimen part, Time
Description
Transcriptional profiling of mouse fibroblast-like synoviocytes (FLS) comparing FLS infected with empty adenovirus and Epas1 adenovirus. RNA was extracted from each FLS. We used microarrays to determine the effect of Epas1 overexpression on FLS and identifying the noble regulatory molecules during r ...See More
Publication Title
Crosstalk between FLS and chondrocytes is regulated by HIF-2α-mediated cytokines in arthritis.
Alternate Accession IDs
E-GEOD-73658Sample Metadata Fields
Specimen part
Description
The jmjC-domain containing H3K4 histone demethylase JARID1B/KDM5B/PLU1 is over-expressed in human breast cancer and is a potential target for breast cancer treatment. To investigate the in vivo function of JARID1B, we developed a new strain of Jarid1b knockout mice and characterized the phenotypes i ...See More
Publication Title
Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes.
Alternate Accession IDs
E-GEOD-50479Sample Metadata Fields
Specimen part
Description
Purpose: The goals of this experiments are to analyze the transcriptomic change in dyrk1aakrb1 mutants compared with WT embryos by mRNA-seq technique. Methods: Whole mRNA profiles of 32 hpf WT(+/+) and dyrk1aakrb1 mutants zebrafish embryos were generated by mRNA-seq techinque, in duplicate, ...See More
Publication Title
Vascular defects of <i>DYRK1A</i> knockouts are ameliorated by modulating calcium signaling in zebrafish.
Alternate Accession IDs
GSE123026Sample Metadata Fields
Age, Specimen part, Subject
Description
Purpose: The goals of this experiments are to analyze the transcriptomic change in dyrk1aakrb1 mutants compared with WT embryos by mRNA-seq technique. Methods: Whole mRNA profiles of 48 hpf WT(+/+) and dyrk1aakrb1 mutants zebrafish embryos were generated by mRNA-seq techinque, in duplicate, ...See More
Publication Title
Vascular defects of <i>DYRK1A</i> knockouts are ameliorated by modulating calcium signaling in zebrafish.
Alternate Accession IDs
GSE111280Sample Metadata Fields
Specimen part, Subject
Description
Tissue inflammation is a key factor underlying insulin resistance in established obesity. Several models of immuno-compromised mice are protected from obesity-induced insulin resistance. However, it is unanswered whether inflammation triggers systemic insulin resistance or vice versa in obesity. The ...See More
Publication Title
Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation.
Alternate Accession IDs
E-GEOD-65557Sample Metadata Fields
Specimen part, Treatment, Time
Description
Human adipose stem cells (ASCs) have been shown, in pre-clinical studies, to have therapeutic applicability in diverse fields, but a standard expansion method for clinical applications remains yet to be established. Isolated ASCs are typically expanded in medium containing fetal bovine serum (FBS). ...See More
Publication Title
Differential gene expression in adipose stem cells cultured in allogeneic human serum versus fetal bovine serum.
Alternate Accession IDs
E-GEOD-17090Sample Metadata Fields
Specimen part
Description
2-methoxyestradiol (2ME2) induces mammary gland differentiation through amphiregulin-EGFR mediated signaling: molecular distinctions from the mammary gland of pregnant mice.High levels of 2ME2 are observed in the late stages of pregnancy. We investigated the role of 2ME2 on normal mammary gland de ...See More
Publication Title
2-methoxyestradiol induces mammary gland differentiation through amphiregulin-epithelial growth factor receptor-mediated signaling: molecular distinctions from the mammary gland of pregnant mice.
Alternate Accession IDs
E-GEOD-70048Sample Metadata Fields
Specimen part, Cell line