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Description
Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in mouse NIH-3T3 cells and RNA-protein complexes isola ...See More
Publication Title
Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each.
Alternate Accession IDs
E-GEOD-64761Sample Metadata Fields
Cell line
Description
Rhabdoid Tumors (RT) are highly aggressive tumors that are frequently localized in the central nervous system (CNS) where they are termed atypical teratoid and rhabdoid tumors (ATRT). We generated conditional Smarcb1-deficient mouse model leads to CNS Smarcb1-deficient tumors.
Publication Title
The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation.
Alternate Accession IDs
E-GEOD-64019Sample Metadata Fields
Specimen part
Description
The role of estrogen and testosterone in the regulation of gene expression in the proximal reproductive tract is not completely understood. To address this question, mice were treated with testosterone or estradiol and RNA from the efferent ducts and caput epididymis was processed and hybridized to ...See More
Publication Title
Regulation of gene expression by estrogen and testosterone in the proximal mouse reproductive tract.
Alternate Accession IDs
E-GEOD-17553Sample Metadata Fields
Sex, Specimen part, Treatment
Description
Expession data from L1-L2 stage nematodes (C. elegans), wild type and four mutants (alg-1, zfp-1, rde-4, lin-35).
Publication Title
RNA interference and retinoblastoma-related genes are required for repression of endogenous siRNA targets in Caenorhabditis elegans.
Alternate Accession IDs
E-GEOD-13258Sample Metadata Fields
No sample metadata fields
Description
WIN 18,446/RA treatment of neonatal mice was used to synchronize the initial wave of spermatogenesis and identify novel messages expressed within either germ or Sertoli cells as spermatogonia enter meiosis.
Publication Title
Riding the spermatogenic wave: profiling gene expression within neonatal germ and sertoli cells during a synchronized initial wave of spermatogenesis in mice.
Alternate Accession IDs
E-GEOD-54408Sample Metadata Fields
Specimen part
Description
Murine testis developmental time course created from tissue samples collected from birth through adulthood and hybridized to MGU74v2 A, B, and C chips in duplicate
Publication Title
The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis.
Alternate Accession IDs
E-GEOD-926Sample Metadata Fields
No sample metadata fields
Description
Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that was identified through its rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice, and cells derived from them, showed that TTP could bind to certain AU-rich elements in mRNAs, leading to increases in the rates of mRN ...See More
Publication Title
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts.
Alternate Accession IDs
E-GEOD-5324Sample Metadata Fields
Cell line
Description
Time course of gene expression in the murine embryonic testis from the time of the indifferent gonad (11.5dpc) to birth (18.5dpc)
Publication Title
Profiling gene expression during the differentiation and development of the murine embryonic gonad.
Alternate Accession IDs
E-GEOD-1358Sample Metadata Fields
No sample metadata fields
Description
Time course of gene expression in the murine embryonic ovary from the time of the indifferent gonad (11.5dpc) to birth (18.5dpc)
Publication Title
Profiling gene expression during the differentiation and development of the murine embryonic gonad.
Alternate Accession IDs
E-GEOD-1359Sample Metadata Fields
No sample metadata fields
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Profiling gene expression during the differentiation and development of the murine embryonic gonad.
Alternate Accession IDs
E-GEOD-6916Sample Metadata Fields
No sample metadata fields