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Homo sapiens
14 Downloadable Samples
Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)
Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.

Alternate Accession IDs
E-GEOD-56897
Sample Metadata Fields

Specimen part, Cell line

Homo sapiens
8 Downloadable Samples
Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)
Description

Aberrant activation of WNT signaling and loss of BMP signals represent the two main alterations leading to the initiation of colorectal cancer (CRC). Here we screen for genes required for maintaining the tumor stem cell phenotype and identify the zinc-finger transcription factor GATA6 as key regulat ...See More

Publication Title

The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.

Alternate Accession IDs
E-GEOD-56895
Sample Metadata Fields

Specimen part, Cell line

Homo sapiens
6 Downloadable Samples
Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)
Description

Aberrant activation of WNT signaling and loss of BMP signals represent the two main alterations leading to the initiation of colorectal cancer (CRC). Here we screen for genes required for maintaining the tumor stem cell phenotype and identify the zinc-finger transcription factor GATA6 as key regulat ...See More

Publication Title

The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.

Alternate Accession IDs
E-GEOD-56896
Sample Metadata Fields

Specimen part, Cell line

Arabidopsis thaliana
8 Downloadable Samples
Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)
Description

Heat stress is one of the most prominent and deleterious environmental threads affecting plant growth and development. Upon high temperatures, plants launch specialized gene expression programs that promote stress protection and survival. These programs involve global and specific changes at the tra ...See More

Publication Title

Analysis of genome-wide changes in the translatome of Arabidopsis seedlings subjected to heat stress.

Alternate Accession IDs
E-GEOD-44053
Sample Metadata Fields

Specimen part

Homo sapiens
6 Downloadable Samples
Affymetrix Human Gene 1.0 ST Array (hugene10st)
Description

We sought to elucidate the molecular mechanisms whereby LIN28B functions by comparing the gene expression profile of cells constitutively expressing LIN28B to empty vector controls.

Publication Title

LIN28B promotes colon cancer progression and metastasis.

Alternate Accession IDs
E-GEOD-26334
Sample Metadata Fields

Disease, Cell line

Rattus norvegicus
12 Downloadable Samples
Affymetrix Rat Gene 2.0 ST Array (ragene20st)
Description

The aim of this experiment is to determine Hhex targets in the presence and absence of Myc.

Publication Title

Growth-promoting and tumourigenic activity of c-Myc is suppressed by Hhex.

Alternate Accession IDs
E-GEOD-51467
Sample Metadata Fields

Cell line

Mus musculus
12 Downloadable Samples
Affymetrix Mouse Gene 1.0 ST Array (mogene10st)
Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure.

Alternate Accession IDs
E-GEOD-66646
Sample Metadata Fields

Sex, Specimen part, Treatment

Mus musculus
6 Downloadable Samples
Affymetrix Mouse Gene 1.0 ST Array (mogene10st)
Description

Mouse models of Fetal Alcohol Spectrum Disorder can be used to assess molecular changes underlying the disorder. Neonatal ethanol exposure in mice can be used to model third trimester ethanol exposure in humans.

Publication Title

Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure.

Alternate Accession IDs
E-GEOD-66644
Sample Metadata Fields

Sex, Specimen part, Treatment

Mus musculus
46 Downloadable Samples
Affymetrix Mouse Genome 430 2.0 Array (mouse4302)
Description

18 different population of cells in different developmental stages in hematopoietic hierarchy have been purifyed by FACS analyses from wild type C57Bl6 mice and subjected to Micrroarray Affymetrix mouse 430.2 platform

Publication Title

CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation.

Alternate Accession IDs
E-GEOD-14833
Sample Metadata Fields

No sample metadata fields

Mus musculus
13 Downloadable Samples
Affymetrix Mouse Gene 1.0 ST Array (mogene10st)
Description

In a pilot experiment to reprogramme MEF into endoderm, we infected MEF with the Yamanakas factors (O: Oct4, K: Klf4, S: Sox2, M:Myc), FoxA2 (F) and Gata4 (G). Global gene expression of isolated clones was performed.

Publication Title

Gata4 blocks somatic cell reprogramming by directly repressing Nanog.

Alternate Accession IDs
E-GEOD-37548
Sample Metadata Fields

No sample metadata fields

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