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Adipose tissue exposed to cold
Description
Cold triggers VEGF dependent but hypoxia independent angiogenesis in adipose tissues and anti-VEGF agents modulate adipose metabolism
Publication Title
Hypoxia-independent angiogenesis in adipose tissues during cold acclimation.
Alternate Accession IDs
E-GEOD-13432Sample Metadata Fields
Sex
Description
Vascular pericytes, an important cellular component, in the tumor microenvironment, are often associated with tumor vasculatures and their functions in cancer invasion and metastasis are poorly understood. Here we show that PDGF-BB induces pericyte fibroblast transition (designated as PFT), which si ...See More
Publication Title
Pericyte-fibroblast transition promotes tumor growth and metastasis.
Alternate Accession IDs
E-GEOD-85955Sample Metadata Fields
Specimen part
Description
Epigenetic mechanisms including histone post-translational modifications control longevity in diverse organisms. Relatedly, loss of proper transcriptional regulation on a global scale is an emerging aspect of shortened lifespan, but the specific mechanisms linking these observations remain to be unc ...See More
Publication Title
H3K36 methylation promotes longevity by enhancing transcriptional fidelity.
Alternate Accession IDs
GSE65764Sample Metadata Fields
Subject
Description
Epigenetic mechanisms including histone post-translational modifications control longevity in diverse organisms. Relatedly, loss of proper transcriptional regulation on a global scale is an emerging aspect of shortened lifespan, but the specific mechanisms linking these observations remain to be unc ...See More
Publication Title
H3K36 methylation promotes longevity by enhancing transcriptional fidelity.
Alternate Accession IDs
GSE65765Sample Metadata Fields
Cell line, Treatment, Subject
Description
High-throughput sequencing was employed to analyze the genes whose expression are altered when lncRNA LAST is downregulated by shRNA in HCT116 cells. The Gencode Gene ID of lncRNA LAST is ENSG00000254682.1. Overall design: In order to identify the genes whose expression levels were changed under the ...See More
Publication Title
<i>LAST</i>, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote <i>CCND1</i> mRNA stability in human cells.
Alternate Accession IDs
GSE106917Sample Metadata Fields
Cell line, Subject
Description
Noncoding RNAs (ncRNAs) are emerging as key molecules in human cancer, with the potential to serve as novel markers of disease and to reveal uncharacterized aspects of tumor biology. Here we discover 121 unannotated prostate cancer–associated ncRNA transcripts (PCATs) by ab initio assembly of high-t ...See More
Publication Title
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression.
Alternate Accession IDs
GSE25183Sample Metadata Fields
No sample metadata fields
Description
Systemic sclerosis (SSc) is a devastating disease affecting the skin and internal organs. Dermal fibrosis manifests early and Modified Rodnan Skin Scores (MRSS) correlate with disease progression. Transcriptomics of SSc skin biopsies suggest the role of the in vivo microenvironment in maintaining th ...See More
Publication Title
Increased dermal collagen bundle alignment in systemic sclerosis is associated with a cell migration signature and role of Arhgdib in directed fibroblast migration on aligned ECMs.
Alternate Accession IDs
GSE100212Sample Metadata Fields
No sample metadata fields
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Tailoring high-density oligonucleotide arrays for transcript profiling of different Arabidopsis thaliana accessions using a sequence-based approach.
Alternate Accession IDs
E-GEOD-94764Sample Metadata Fields
Specimen part
Description
In order to identify differentially expressed genes in developing seeds of Arabidopsis thaliana three different stages of seed development were analysed (9-10, 10-11 and 12-13 days after flower opening) for two Arabidopsis thaliana accessions, Col-0 and C24. For each stage and accession three biolog ...See More
Publication Title
Tailoring high-density oligonucleotide arrays for transcript profiling of different Arabidopsis thaliana accessions using a sequence-based approach.
Alternate Accession IDs
E-GEOD-94763Sample Metadata Fields
Specimen part
Description
In order to identify differentially expressed genes in developing seeds of Arabidopsis thaliana three different stages of seed development were analysed (9-10, 10-11 and 12-13 days after flower opening) for two Arabidopsis thaliana accessions, Col-0 and C24. For each stage and accession three biolog ...See More
Publication Title
Tailoring high-density oligonucleotide arrays for transcript profiling of different Arabidopsis thaliana accessions using a sequence-based approach.
Alternate Accession IDs
E-GEOD-94762Sample Metadata Fields
Specimen part