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Description
Gene expression study of DSG2 silenced human microvascular endothelial cells
Publication Title
Desmoglein-2-integrin Beta-8 interaction regulates actin assembly in endothelial cells: deregulation in systemic sclerosis.
Alternate Accession IDs
E-GEOD-21547Sample Metadata Fields
Specimen part
Description
Determine the effect of miR-203 expression on the global mRNA expression in mesenchymal breast cancer cell line.
Publication Title
Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties.
Alternate Accession IDs
E-GEOD-50697Sample Metadata Fields
Specimen part, Cell line, Treatment
Description
Peripheral T-cell lymphoma unspecified (PTCL/U), the most common form of PTCL, displays heterogeneous morphology and phenotype, poor response to treatment, and dismal prognosis. We demonstrate that PTCL/U shows a gene expression profile clearly distinct from that of normal T-cells. Comparison with t ...See More
Publication Title
Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets.
Alternate Accession IDs
E-GEOD-6338Sample Metadata Fields
No sample metadata fields
Human CRC cell populations
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation.
Alternate Accession IDs
E-GEOD-39397Sample Metadata Fields
Specimen part, Disease, Disease stage, Treatment, Subject
Description
The survival of isolated metastatic cells and expansion into macroscopic tumour has been recognized as a limiting step for metastasis formation in several cancer types yet the determinants of this process remain largely uncharacterized. In colorectal cancer (CRC), we identify a transcriptional progr ...See More
Publication Title
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation.
Alternate Accession IDs
E-GEOD-39395Sample Metadata Fields
Specimen part, Disease, Disease stage, Subject
Description
The survival of isolated metastatic cells and expansion into macroscopic tumour has been recognized as a limiting step for metastasis formation in several cancer types yet the determinants of this process remain largely uncharacterized. In colorectal cancer (CRC), we identify a transcriptional progr ...See More
Publication Title
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation.
Alternate Accession IDs
E-GEOD-39396Sample Metadata Fields
Disease, Disease stage, Subject
Description
The survival of isolated metastatic cells and expansion into macroscopic tumour has been recognized as a limiting step for metastasis formation in several cancer types yet the determinants of this process remain largely uncharacterized. In colorectal cancer (CRC), we identify a transcriptional progr ...See More
Publication Title
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation.
Alternate Accession IDs
E-GEOD-39394Sample Metadata Fields
Specimen part, Treatment
Description
The Wnt gene family is an evolutionarily conserved group of proteins that regulate cell growth, differentiation, and stem cell self-renewal. Aberrant Wnt signaling in human breast tumors has been proposed to be an attractive drug target, especially in the basal-like subtype where canonical Wnt signa ...See More
Publication Title
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Alternate Accession IDs
GSE118163Sample Metadata Fields
Specimen part, Subject
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Targeted resequencing identifies PTCH1 as a major contributor to ocular developmental anomalies and extends the SOX2 regulatory network.
Alternate Accession IDs
E-GEOD-74600Sample Metadata Fields
Specimen part, Time
Description
Here we show that the histone methyltransferase MLL4 (Kmt2d) is required for stem cell activity and an aggressive form of acute myeloid leukemia (AML) harboring the MLL-AF9 oncogene. MLL4 exerts its function by regulating transcriptional programs associated with the anti-oxidant response. Overall de ...See More
Publication Title
DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.
Alternate Accession IDs
GSE57147Sample Metadata Fields
No sample metadata fields