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10X-based scRNA-seq data human fetal kidneys at 5 different ages Overall design: w9, w11, w13, w16 and w18 human fetal kidneys
Publication Title
Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development.
Alternate Accession IDs
GSE114530Sample Metadata Fields
Specimen part, Subject
Description
Skeletal muscle atrophy is a consequence of many diseases, environmental insults, inactivity, age and injury. Atrophy is characterized by active degradation and removal of contractile proteins and a reduction in fiber size. Animal models have been extensively used to identify pathways leading to a ...See More
Publication Title
Distinct protein degradation profiles are induced by different disuse models of skeletal muscle atrophy.
Alternate Accession IDs
E-GEOD-25908Sample Metadata Fields
Sex, Specimen part, Treatment, Time
Description
All highly and poorly permeable metastases from the same mouse brain were collected by laser capture microdissection. Total RNA from both metastatic lesions and immediate microenvironment was isolated from 5 mice bearing 231-BR metastases. As control 4 healthy mouse brains were included.
Publication Title
Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases.
Alternate Accession IDs
E-GEOD-112776Sample Metadata Fields
Subject
Description
Deregulated expression of the Myc transcription factor is a frequent causal mutation in human cancer. Thousands of putative Myc target genes have been identified in in vitro studies, indicating that Myc exerts highly pleiotropic effects within cells and tissues. However, the complexity and diversity ...See More
Publication Title
Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.
Alternate Accession IDs
E-GEOD-4356Sample Metadata Fields
No sample metadata fields
Description
We have generated stable human ESCs (H9) expressing control or DAP5-targeting shRNA. Polysome profiles reveal no major changes in overall translation. PolyA+ RNA and RNA accociated with heavy polysomal fractions were purified in biological duplicates and sequenced using Illumina HiSeq 2000 instrumen ...See More
Publication Title
Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells.
Alternate Accession IDs
GSE80467Sample Metadata Fields
Subject
Description
Background: Cerebral ischemia/reperfusion injury is a common secondary effect of cardiac arrest which is largely responsible for postresuscitative mortality. Therefore development of therapies which restore and protect the brain function after cardiac arrest is essential. Methylene blue (MB) has be ...See More
Publication Title
Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress.
Alternate Accession IDs
E-GEOD-22165Sample Metadata Fields
Specimen part
Description
The ubiquitin proteasome system (UPS) is known to possess important regulatory functions in the immune response. To gain a better and first comprehensive insight into the mechanisms of remodelling of UPS related gene expression inresponse to interferon-gamma, we undertook a comparative gene express ...See More
Publication Title
Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress.
Alternate Accession IDs
E-GEOD-21760Sample Metadata Fields
Specimen part, Time
Description
A cell supsension containing an equal mix of HEK and 3T3 cells was used in the Fluidigm C1 Overall design: Suspensions of 3T3 and HEK cells were diluted down to a concentration of 250,000 per mL and mixed 1:1, then loaded onto two medium C1 cell capture chips.
Publication Title
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets.
Alternate Accession IDs
GSE70151Sample Metadata Fields
No sample metadata fields
Description
RNAseq analysis of YAP and Myc induced in quiescent and confluent 3T9 fibroblasts Overall design: RNAseq analysis of YAP and Myc induced in quiescent and confluent 3T9 fibroblasts
Publication Title
Transcriptional integration of mitogenic and mechanical signals by Myc and YAP.
Alternate Accession IDs
GSE83867Sample Metadata Fields
Specimen part, Cell line, Subject
Description
Tumors driven by activation of the transcription factor Myc generally show oncogene addiction. However, the gene-expression programs that depend upon sustained Myc activity in those tumors remain unknown. We have addressed this issue in a model of liver carcinoma driven by a reversible tet-Myc trans ...See More
Publication Title
Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors.
Alternate Accession IDs
GSE76062Sample Metadata Fields
Specimen part, Cell line, Subject