GSE106981

Expression data from thymic non-hematopoietic stromal cells after damage

Mus musculus
9 Downloadable Samples
Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description
The thymus is extremely sensitive to damage but also has a remarkable ability to repair itself. However, the mechanisms underlying this endogenous regeneration remain poorly understood and this capacity diminishes considerably with age. To identify alternate regeneration pathways in the thymus, we performed an unbiased transcriptome analysis of the non-hematopoietic (CD45-) stromal cell compartment of the thymus, which is less sensitive to thymic damage compared to the CD45+ hematopoietic compartment.
PubMedID
29330161
Publication Title
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.
Total Samples
9
Submitter’s Institution
Authors
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Source Repositories
Gene Expression Omnibus (GEO)
Alternate Accession IDs
E-GEOD-106981

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